AOBIOME / Mother DirtArticles & NewsHomeAOBiome Therapeutics Granted Composition of Matter Patent for its Clinical CandidateOnce deployed on the skin, AOB converts ammonia to nitrite, which is known to have antibacterial properties, and to nitric oxide, a signaling molecule known to regulate inflammation and vasodilation.HomeAOBiome's Topical B244 Yields Pivotal Phase 2b Results for Pruritus, Eczema"The efficacy observed after only 4 weeks is exciting; ... an effective non-steroidal, non-injectable therapy without black box warnings or laboratory monitoring is pretty much the holy grail..."HomePatent Pick: Microorganisms to Modulate Skin pHAmmonia oxidizing microorganisms are the subject of a novel patent application from AOBiome, described herein to impart skin benefits by controlling pH.